Vaccine Lab / Alfa Chemistry
N-TETAMINE-pSar35

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N-TETAMINE-pSar35

Catalog Number ACM2847775931-1
CAS 2847775-93-1
Structure
Description N,N-ditetradecylamine-N-succinyl[methyl(polysarcosine)35]
Polypeptoid-lipid conjugates based on the amino acid sarcosine (pSar) have become a promising alternative to PEGylated lipids. When formulating LNPs, pSar lipids of varying polymeric chain lengths have been used to tune physical properties such as particle size, morphology, and internal structure.
Not only are they used to alter the physical characteristics of LNPs, but pSar LNPs have also proven to be an excellent mRNA transfection agent. Comparing pSar lipid to PEGylated lipid LNP formulations showed a more robust mRNA transfection potency while also improving the safety profile.
Molecular Weight 2897.55
Molecular Formula C133H234N36O35
Purity >99%
Exact Mass 2895.76
Form Powder
Hygroscopic No
Light Sensitive No
Percent Composition C 55.13%, H 8.14%, N 17.40%, O 19.33%
Stability 1 Year
Storage Temperature -20℃
Type Polysarcosine (pSar) Lipids
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