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| Target | SARS-CoV-2 Spike S2 |
| Target Type | Viral Protein |
| Protein Type | Recombinant |
| Origin | SARS-CoV-2 |
| Source | HEK-293 Cells |
| Purification Tag | This product is labelled with His tag. |
| Purity | > 95 % as determined by SDS-PAGE |
| Molecule Mass | The protein has a predicted MW of 60.0 kDa. |
| Endotoxin Level | Less than 1.0 EU per μg by the LAL method. |
| Formulation | Supplied as 0.2 μm filtered solution in 20 mM PB, 300 mM NaCl, pH7.4. |
| Application Notes | This product is specifically designed for serological test development. |
| Shipping | This product is shipped in dry ice unless customers require otherwise. |
| Storage | This product can be stored stably for one year under sterile conditions from −20 to −80 °C. Please avoid freeze-thaw cycles. |
The spike (S) protein of coronavirus is the main target for the development of vaccines and a potential strategy to counteract viral entry into human cells. The S protein forms a trimer at the protrusion of the virus and consists of two functional subunits: S1 and S2 [1]. Among them, the S2 domain mediates membrane fusion. In addition to mediating virus entry, the spike is a critical determinant of viral host range and tissue tropism and a major inducer of host immune responses [2].
Figure 1. Realistic three-dimensional illustration of COVID-19 virus structure diagram. The red box labeled part is the spike protein, which is the main structural component of the coronavirus virion.
Since the SARS-CoV-2 pandemic, research into the detection and treatment of Coronavirus has never stopped. Alfa Chemistry is committed to providing customers with a series of antigens for diagnostics to meet the various needs of customers. If the product you are looking for is not in our catalog, please contact us. We will be happy to provide you with customized synthesis services.
Our products and services are for research use only and cannot be used for any clinical purposes.
Alfa Chemistry is a global leader in the vaccine industry. We have the ability to help our customers meet the challenges of various vaccine development processes. Alfa Chemistry believes that partnerships will change the way the world innovates, bringing new technologies.
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