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| Target | SARS-CoV-2 Spike |
| Target Type | Viral Protein |
| Protein Type | Recombinant |
| Origin | SARS-CoV-2 |
| Source | HEK-293 Cells |
| Predicted N Terminal | Val 16 |
| Purification Tag | This product is labelled with His tag. |
| Purity | > 95 % as determined by SDS-PAGE > 90 % as determined by SEC-MALS |
| Molecule Mass | The protein has a predicted MW of 138.0 kDa. |
| Endotoxin Level | Less than 1.0 EU per μg by the LAL method. |
| Formulation | Supplied as 0.2 μm filtered solution in PBS. |
| Application | ELISA |
| Application Notes | This product is specifically designed for serological test development. |
| Shipping | This product is shipped in dry ice unless customers require otherwise. |
| Storage | This product can be stored stably for one year under sterile conditions from −20 to −80 °C. Please avoid freeze-thaw cycles. |
The spike (S) protein of coronavirus is the main target for the development of vaccines and a potential strategy to counteract viral entry into human cells. The S protein forms a trimer at the protrusion of the virus and consists of two functional subunits: S1 and S2 [1]. The S protein mediates viral entry into host cells by first binding to a host receptor through the receptor-binding domain (RBD) in the S1 subunit and then fusing the viral and host membranes through the S2 subunit [2].
Figure 1. Realistic three-dimensional illustration of COVID-19 virus structure diagram. The red box labeled part is the spike protein, which is the main structural component of the coronavirus virion.
Since the SARS-CoV-2 pandemic, research into the detection and treatment of Coronavirus has never stopped. Alfa Chemistry is committed to providing customers with a series of antigens for diagnostics to meet the various needs of customers. If the product you are looking for is not in our catalog, please contact us. We will be happy to provide you with customized synthesis services.
Our products and services are for research use only and cannot be used for any clinical purposes.
Alfa Chemistry is a global leader in the vaccine industry. We have the ability to help our customers meet the challenges of various vaccine development processes. Alfa Chemistry believes that partnerships will change the way the world innovates, bringing new technologies.
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