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CONTACT US| Catalog Number | ACM151213-2 |
| CAS | 151-21-3 |
| Structure |  |
| Description | Sodium dodecyl sulfate, synonymously sodium lauryl sulfate (or laurilsulfate; SDS or SLS, respectively), is a synthetic organic compound with the formula CH3(CH2)11SO4Na. It is an anionic surfactant used in many cleaning and hygiene products. The sodium salt is of an organosulfate class of organics. It consists of a 12-carbon tail attached to a sulfate group,[not verified in body] i.e., it is the sodium salt of dodecyl hydrogen sulfate, the ester of dodecyl alcohol and sulfuric acid. Its hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties and so make it useful as a detergent.[not verified in body] Also derived as a component of mixtures produced from inexpensive coconut and palm oils, SDS is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations.[not verified in body] |
| Synonyms | Aquarexmethyl |
| IUPAC Name | Sodium;dodecyl sulfate |
| Molecular Weight | 288.38 |
| Molecular Formula | C12H25NaO4S |
| Canonical SMILES | CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+] |
| InChI | InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1 |
| InChI Key | DBMJMQXJHONAFJ-UHFFFAOYSA-M |
| Boiling Point | 216 °C |
| Melting Point | 204-207 °C(lit.) |
| Flash Point | >100 °C |
| Purity | 98% |
| Density | 1.03 g/mL at 20 °C |
| Solubility | Soluble in water |
| Appearance | Powder or crystals |
| Application | Leather assistant, plastic auxiliaries, biocide |
| Storage | 2-8 °C |
| Complexity | 249 |
| Covalently-Bonded Unit Count | 2 |
| Critical Micelle Concentration | 7-10 mM (25°C) |
| Defined Atom Stereocenter Count | 0 |
| EC Number | 205-788-1 |
| Exact Mass | 288.13712473 |
| Heavy Atom Count | 18 |
| Hydrogen Bond Acceptor Count | 4 |
| Hydrogen Bond Donor Count | 0 |
| Isomeric SMILES | CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+] |
| LogP | 4.46490 |
| MDL Number | MFCD00036175 |
| Monoisotopic Mass | 288.13712473 |
| pH | 6-9 |
| Physical State | Solid |
| Rotatable Bond Count | 12 |
| Stability | Stable under normal temperatures and pressures. |
| Storage Conditions | Room temperature |
| Topological Polar Surface Area | 74.8 Ų |
| WGK Germany | 2 |
Zhang L, et al. Angew Chem Int Ed Engl, 2015, 54(33), 9533-9536.
Ultrastable foams can be created by combining sodium dodecyl sulphate with a salt, such as NaCl or KCl. The addition of a high concentration of salt causes the surfactant to precipitate on the surface of the bubbles and form crystals in the interstices between the bubbles. This process halts the ageing of the foams, making them stable indefinitely, or until they are heated above the melting point of the crystals.
Using KCl has proven to be more effective than NaCl because potassium dodecyl sulphate has a higher melting point and crystallizes more rapidly. The crystal structure inside the foam was analyzed using small angle neutron scattering. It was found that crystals formed with NaCl have a larger lattice spacing compared to those formed with KCl.
This method provides a simple way to create very stable foams. These foams can be used in applications where the shelf life of a product needs to be measured in months or years without degrading the quality of the foam. Additionally, because they are temperature sensitive, they can serve as simple temperature sensors to indicate prolonged heating during transport. However, their primary advantages are their simplicity, ultra-stability, and responsiveness, which make them suitable for a wide range of applications.
Yu H, et al. Materials Science and Engineering: B, 2023, 298, 116890.
A Ni-SDS-PbO2 electrode, co-doped with nickel (Ni) and sodium dodecyl sulfate (SDS), can be prepared using TiO2 nanotubes as a substrate through a simple electrodeposition method. This electrode exhibits an accelerated electrocatalytic degradation rate for tetracycline.
The preparation method is as follows:
Ti Sheet Preparation: A Ti sheet (purity > 99.5%) is polished with sandpapers and chemically etched in a solution of HF/HNO3/H2O (1:4:5 v/v). The sheet is then ultrasonically cleaned in acetone and deionized water sequentially.
TiO2 Nanotube Film Formation: Anodize the pretreated Ti sheet at 25 V for 2 hours in a glycerol solution containing 0.5% NH4F. Anneal the resulting TiO2 nanotube film at 500 °C for 2 hours.
PbO2 Surface Layer Preparation: Electrodeposit a layer of α-PbO2 in a solution of 3.5 M NaOH and 0.1 M PbO at 10 mA·cm-2 for 60 minutes, using the TiO2 nanotube film as the anode and a Pb plate as the cathode. Electrodeposit a layer of β-PbO2 doped with Ni and SDS on α-PbO2 at 30 mA·cm-2 for 60 minutes in a solution containing 0.1 M HNO3, 0.5 M Pb(NO3)2, 0.05 M NaF, Ni(NO3)2·6H2O (Ni/Pb = 1 at%), and 0.7 mM SDS. The resulting electrode is designated as Ni-SDS-PbO2.
Li A, et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 687, 133515.
Sodium dodecyl sulfate (SDS) can be utilized as a raw material to synthesize Li1.2Ni0.13Co0.13Mn0.54O2 (S-LRMC), a lithium-rich manganese-based cathode material with a continuous Na2SO4 coating. Initially, SDS forms micelle-like adsorption coatings on the surfaces of LRMC in an aqueous solution. After a calcination process, a uniform Na2SO4 continuous coating is formed on the Li1.2Ni0.13Co0.13Mn0.54O2 surface.
Mechanism:
SDS, consisting of hydrophobic aliphatic hydrocarbon groups and hydrophilic sulfate groups, creates micelle-like encapsulation layers on the LRMC surface in an aqueous solution. The uniform Na2SO4 capping layer formed after calcination effectively inhibits side reactions between the electrode material and the electrolyte, reducing the dissolution of transition metal ions. This improves the capacity retention rate, multiplicity performance, and discharge specific capacity.
Preparation Steps:
SDS Solution Preparation: Dissolve an appropriate amount of SDS in deionized water to ensure complete dispersion.
Suspension Formation: Add 1g of LRMC sample powder to the SDS solution to create a suspension. Transfer the suspension to a PTFE reactor and react at 120 °C for 2 hours to form a homogeneous monolayer of SDS on the LRMC surface.
Drying and Calcination: Filter the reaction products and dry them at 80 °C for 12 hours. Temper the dried samples in air at 750 °C for 5 hours. The final product is the continuous Na2SO4-coated lithium-rich manganese cathode material Li1.2Ni0.13Co0.13Mn0.54O2 (S-LRMC).
Qin Y, et al. Analytica Chimica Acta, 2024, 1311, 342736.
Sodium dodecyl sulfate (SDS) can be used for the development of Offline-Online capillary electrophoresis (CE) stacking strategies. This method integrates micro solid-phase dispersion (MSPD) extraction with field-amplified sample stacking (FASS) and micelle to cyclodextrin stacking (MCDS). SDS plays a crucial role as both the extraction solvent and the micelle agent for MCDS stacking. This method offers a simple, efficient, and green analytical method for the simultaneous determination of key compounds in L. aggregata and rat feces.
Capillary Conditioning
New capillaries: Rinsed with 1.0 M NaOH (20 min), 0.1 M NaOH (10 min), and purified water (10 min).
Run-to-run conditioning: Rinsed with 0.1 M NaOH (3 min), purified water (3 min), and background electrolyte (BGE) (3 min).
Background Electrolyte (BGE) Composition:100 mM SDS, 65 mM NaH2PO4, 50 mM H3PO4, 35% methanol
Cyclodextrin (CD) Solution: 50 mM HP-β-CD in 100 mM H3PO4
Injection and Detection:
BGE-filled capillary was sequentially injected with CD solution (210 s), pure water (2 s), and injected solution (180 s) at 50 mbar.
A negative voltage of -20 kV was applied.
Capillary temperature: 25°C
Detection wavelength: 205 nm
Typical Analyte Injection:
Hydrodynamic injection at 50 mbar for 3 s.
Mixed standard solution concentration: 200 μg/mL.
Preparation of Standard Solutions
Stock solutions of dehydrocostus lactone, linderane, and norisoboldine were prepared in methanol at 1.0 mg mL⁻¹ each.
Mixed sample solution: 5 μg mL⁻¹ in 20 mM SDS.
Mixed standard solution: 200 μg mL⁻¹ in methanol for typical injection, stored at 4°C.
Preparation of Sample Solutions
Conventional Extraction:
Linderane: L. aggregata root powder (1.5 g) was extracted using 150 mL of diethyl ether in a Soxhlet extractor for 4 hours. The extract was evaporated and re-dissolved in 150 mL of 20 mM SDS.
Norisoboldine: L. aggregata root powder (1.5 g) was extracted with a methanol-hydrochloric acid solution (2:1) under heat reflux for 1 hour. The extract was concentrated and re-dissolved similarly.
SDS-Assisted MSPD Extraction:
L. aggregata root powder (10 mg) and MCM-48 (10 mg) were ground together in an agate mortar for 180 s.
The mixture was placed in a solid-phase extraction cartridge and eluted with 1 mL of 20 mM SDS solution.
All extract solutions were centrifuged at 11,000 rpm for 5 min, and the supernatants were diluted for CE analysis.
What is the molecular weight of Sodium Dodecyl Sulfate?
The molecular weight of Sodium Dodecyl Sulfate is 288.38 g/mol.
What is the role of Sodium Dodecyl Sulfate?
Sodium Dodecyl Sulfate has a role as a detergent and a protein denaturant.
What are some synonyms for Sodium Dodecyl Sulfate?
Some synonyms for Sodium Dodecyl Sulfate include Sodium lauryl sulfate, Sodium dodecylsulfate, and Sodium lauryl sulphate.
What is the IUPAC Name of Sodium Dodecyl Sulfate?
The IUPAC Name of Sodium Dodecyl Sulfate is sodium;dodecyl sulfate.
What is the Canonical SMILES of Sodium Dodecyl Sulfate?
The Canonical SMILES of Sodium Dodecyl Sulfate is CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+].
What is the CAS number for Sodium Dodecyl Sulfate?
The CAS number for Sodium Dodecyl Sulfate is 151-21-3.
How does Sodium Dodecyl Sulfate appear physically?
Sodium Dodecyl Sulfate appears as white to pale yellow paste or liquid with a mild odor.
Where can Sodium Dodecyl Sulfate be used?
Sodium Dodecyl Sulfate is used as a fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals, and toothpastes.
What is the molecular formula of Sodium Dodecyl Sulfate?
The molecular formula of Sodium Dodecyl Sulfate can be NaSO4C12H25, C12H25O4S.Na, or C12H25NaO4S.
What is the role of Sodium Dodecyl Sulfate in protein biochemistry?
Sodium Dodecyl Sulfate is used as a research tool in protein biochemistry.
What is the CAS number of Sodium Dodecyl Sulfate?
The CAS number of Sodium Dodecyl Sulfate is 151-21-3.
Where is Sodium Dodecyl Sulfate used?
Sodium Dodecyl Sulfate is used in cosmetics, pharmaceuticals, toothpastes, and as a research tool in protein biochemistry.
What is the description of Sodium Dodecyl Sulfate according to the U.S. Coast Guard?
Sodium Dodecyl Sulfate appears as a white to pale yellow paste or liquid with a mild odor, and sinks and mixes with water.
What is the parent compound and component compounds of Sodium Dodecyl Sulfate?
The parent compound of Sodium Dodecyl Sulfate is Lauryl sulfate (CID 8778), and the component compounds are Lauryl sulfate (CID 8778) and Sodium (CID 5360545).
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