What is lysine?
Lysine is an α-amino acid that is a precursor to many proteins.
What is the structure of lysine?
Lysine contains an α-amino group, an α-carboxylic acid group, and a side chain lysyl.
How is lysine classified?
Lysine is classified as a basic, charged, aliphatic amino acid.
Can the human body synthesize lysine?
No, the human body cannot synthesize lysine. It must be obtained from the diet.
What are the two main biosynthetic pathways for lysine synthesis?
The two main biosynthetic pathways for lysine synthesis are the diaminopimelate (DAP) pathway and the α-aminoadipate (AAA) pathway.
What are the roles of lysine in humans?
Lysine plays several roles in humans, including proteinogenesis, crosslinking of collagen polypeptides, uptake of essential mineral nutrients, production of carnitine, and histone modifications.
What are the consequences of a lack of lysine?
A lack of lysine can lead to defective connective tissues, impaired fatty acid metabolism, anaemia, and systemic protein-energy deficiency.
What are the consequences of an overabundance of lysine?
An overabundance of lysine, caused by ineffective catabolism, can cause severe neurological disorders.
How is lysine synthesized in organisms?
Lysine is synthesized in organisms through the diaminopimelate (DAP) pathway or the α-aminoadipate (AAA) pathway.