Vaccine Lab / Alfa Chemistry

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Catalog Number ACM56815
CAS 56-81-5
Description Glycerol (also called glycerine or glycerin; see spelling differences) is a simple polyol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in all lipids known as triglycerides. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol has three hydroxyl groups that are responsible for its solubility in water and its hygroscopic nature.
Synonyms Glycerin(mist)
IUPAC Name Propane-1,2,3-triol
Molecular Weight 92.09
Molecular Formula C3H8O3
Canonical SMILES C(C(CO)O)O
InChI InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
Boiling Point 290 °C
Melting Point 20 °C(lit.)
Flash Point 320 °F
Purity 99%+
Density 1.25 g/mL(lit.)
Solubility Insoluble in fixed, volatile oils
Appearance Liquid
Storage 5-30 °C
Complexity 25.2
Covalently-Bonded Unit Count 1
Defined Atom Stereocenter Count 0
Exact Mass 92.047344113
Heavy Atom Count 6
Hydrogen Bond Acceptor Count 3
Hydrogen Bond Donor Count 3
LogP -1.66810
MDL Number MFCD00004722
Monoisotopic Mass 92.047344113
Physical State Viscous liquid
Rotatable Bond Count 2
Stability Stable. Incompatible with perchloric acid, lead oxide, acetic anhydride, nitrobenzene, chlorine, peroxides, strong acids, strong bases. Combustible.
Storage Conditions 5-30 °C
Topological Polar Surface Area 60.7 Ų
WGK Germany 1
Knowledge & Learning Q&A

Source of Glycerol and Its Use in Vaccine Manufacturing

Glycerol has many applications in vaccine formulation, storage and transportation. It can stabilize, protect and improve the overall quality and effectiveness of vaccines and plays a vital role in vaccine production. Get more information on:

  • Glycerin in Vaccine Formulation
    Glycerin can be used in vaccine formulations as stabilizer, antifreeze, lubricant, excipient, and cryoprotectant.
  • Source of Glycerin
    Glycerol can be obtained through a variety of reactions, such as transesterification reaction, saponification reaction, and hydrolysis reaction.

What is glycerol used for?

Glycerol is used as a solvent, sweetening agent, and medicine.

How does glycerol relieve constipation?

Glycerol attracts water into the gut, softening stools and relieving constipation.

Is there scientific evidence to support the use of glycerol for stroke, obesity, and ear infections?

No, there is no good scientific evidence to support these uses.

Why is glycerol banned by the World Anti-Doping Agency?

It is banned because it may enhance athletic performance by attracting water into the blood, helping athletes exercise for longer.

What is glycerol likely effective for?

Glycerol is likely effective for treating constipation in both adults and children.

Can glycerol improve athletic performance?

Taking glycerol with water may help keep the body hydrated during exercise, but it is unclear if it can improve athletic performance.

What skin condition can glycerol potentially treat?

Glycerol, when applied to the skin in a specific product, may reduce symptoms of itching and scales in children with ichthyosis.

Can glycerol reduce the risk of death and seizures in people with bacterial meningitis?

No, taking glycerol by mouth does not reduce the risk of death or seizures in bacterial meningitis patients.

Are there any side effects of taking glycerol orally?

Possible side effects of taking glycerol orally include headaches, dizziness, bloating, nausea, and diarrhea.

Is glycerol safe to use during pregnancy and breastfeeding?

There is not enough reliable information to determine if glycerol is safe to use during pregnancy or breastfeeding, so it is recommended to avoid use.

Our products and services are for research use only and cannot be used for any clinical purposes.

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