Vaccine Lab / Alfa Chemistry
tri-GalNAc-DBCO

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tri-GalNAc-DBCO

Catalog Number ACMA00049964
Description tri-GalNAc-DBCO can bind to the desialic acid glycoprotein receptor (ASGPR) to drive protein downregulation and target protein degradation, where GalNAc is a high-affinity ligand for hepatocyte-specific ASGPR.
Molecular Weight 1730.94
Molecular Formula C82H127N11O29
Canonical SMILES O=C(NCCCNC(CCCCO[C@H](O[C@@H]1CO)[C@@H]([C@H]([C@H]1O)O)NC(C)=O)=O)CCOCC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@H]2O)O)NC(C)=O)=O)=O)(NC(CCCCC(N3CC4=CC=CC=C4C#CC5=CC=CC=C53)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]6CO)[C@@H]([C@H]([C@H]6O)O)NC(C)=O)=O)=O
Purity 0.9992
Solubility 10 mM in DMSO
Form Solid
Stability 1 Year
Storage Temperature Store at -20℃
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