CAS 124050-77-7 Transfectam - Vaccine Lab / Alfa Chemistry

Common Cationic Lipids and Their Applications in Vaccines

Messenger RNA (mRNA) vaccines have emerged as a groundbreaking tool in the realm of vaccine development. Unlike traditional vaccines, mRNA vaccines work by introducing genetic material encoding a specific antigen into cells, prompting the cells to produce the antigen themselves. This approach stimulates an immune response as the body identifies the antigen as foreign and generates antibodies to combat it. One of the key benefits of mRNA vaccines is their agility in design and production, allowing for rapid response to emerging threats such as viral outbreaks or mutations. Get more information on:

Role of mRNA in Vaccine Development
Importance of Cationic Lipids in mRNA Delivery
Cationic Lipids in mRNA Vaccine Formulations
Popular Cationic Lipids from Alfa Chemistry
Examples of Cationic Lipids Utilized in Vaccines

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Catalog Number	ACM124050777-1
CAS	124050-77-7
Structure
Synonyms	Dioctadecylamidoglycylspermine
IUPAC Name	(2S)-2,5-Bis(3-aminopropylamino)-N-[2-(dioctadecylamino)acetyl]pentanamide
Molecular Weight	807.4
Molecular Formula	C49H102N6O2
Canonical SMILES	CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CC(=O)NC(=O)C(CCCNCCCN)NCCCN
InChI	InChI=1S/C49H102N6O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44-55(45-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-48(56)54-49(57)47(53-43-37-40-51)38-35-41-52-42-36-39-50/h47,52-53H,3-46,50-51H2,1-2H3,(H,54,56,57)/t47-/m0/s1
InChI Key	OPCHFPHZPIURNA-MFERNQICSA-N
Purity	98%+
Complexity	779
Covalently-Bonded Unit Count	1
Defined Atom Stereocenter Count	1
Exact Mass	806.80642652
Heavy Atom Count	57
Hydrogen Bond Acceptor Count	7
Hydrogen Bond Donor Count	5
Isomeric SMILES	CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CC(=O)NC(=O)[C@H](CCCNCCCN)NCCCN
Monoisotopic Mass	806.80642652
Physical State	Solid
Rotatable Bond Count	48
Storage Conditions	-20 °C
Topological Polar Surface Area	126 Å²