Vaccine Lab / Alfa Chemistry
Polymyxin B Sulfate

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Polymyxin B Sulfate

Catalog Number ACM1405205-2
CAS 1405-20-5
Structure
Description Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo.
Molecular Weight 1287.53 (PolymyxinB2Sulfate)
Molecular Formula C111H196N32O30S
Purity 0.9812
Appearance Solid
Storage 4°C, sealed storage, away from moisture
In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Initial Source Bacillus polymyxa
Research Areas Infection
Shipping Room temperature in continental US; may vary elsewhere.
Solvent&Solubility In Vitro:
DMSO : 33.33 mg/mL (Need ultrasonic)
H2O : 16.67 mg/mL (Need ultrasonic)
In Vivo:
1. Add each solvent one by one: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline
Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution
2. Add each solvent one by one: 10% DMSO, 90% (20% SBE-β-CD in saline)
Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution
3. Add each solvent one by one: 10% DMSO, 90% corn oil
Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution
Target Antibiotic; Bacterial
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