Monophosphoryl Lipid A-504

Catalog Number	ACMA00049957
Description	Monophosphoryl Lipid A-504 was designed as a synthetic structural analog of detoxified MPLA derived from E. coli lipopolysaccharide (LPS). It is structurally similar to Monophosphoryl Lipid A, differing only in the length of a single fatty acid chain. As expected, the activity of Monophosphoryl Lipid A-504 is quite similar to that of Monophosphoryl Lipid A, making the two products interchangeable as adjuvants in vaccine or immunotherapy formulations.
Molecular Weight	1735.42
Molecular Formula	C94H180 N3O22P
Purity	>99%
Solubility	The solubility in ethanol (as well as other alcohols) and DMSO is limited. Additionally, this species is insoluble in water (aqueous buffers, serum etc.); however, it can be dispersed in an aqueous medium using a suitable emulsifier or detergent. This species is soluble in chloroform (at least up to 50 mg/mL) and chloroform:methanol solvent systems, however gentle heating and sonication may be necessary to aid in dissolution. Dropwise additions of methanol or water may aid dissolution in chloroform at higher concentrations. If using in combination with other lipids, dissolve this lipid separately and then combine dissolved lipids in their respective solvent solutions.
Exact Mass	1734.28
Form	Powder
Hygroscopic	No
Light Sensitive	No
Percent Composition	C 65.06% H 10.45% N 2.42% O 20.28% P 1.78 %
Stability	1 year
Storage Temperature	-20℃
Type	TLR-4 Agonist

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Monophosphoryl Lipid A-504 (ACMA00049957)

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