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Monophosphoryl Hexa-acyl Lipid A, 3-Deacyl
Catalog Number |
ACMA00049956 |
Description |
As with other synthetic MPLA analogs, it is structurally homogeneous and highly purified and mimics the TLR4 agonist activity of bacterial MPLA. |
Molecular Weight |
1747.469 |
Molecular Formula |
C96H184N3O21P |
Purity |
>99% |
Solubility |
The solubility in ethanol (as well as other alcohols) and DMSO is limited. Additionally, this species is insoluble in water (aqueous buffers, serum etc.); however, it can be dispersed in an aqueous medium using a suitable emulsifier or detergent. This species is soluble in chloroform (at least up to 50 mg/mL) and chloroform:methanol solvent systems, however gentle heating and sonication may be necessary to aid in dissolution. Dropwise additions of methanol or water may aid dissolution in chloroform at higher concentrations. If using in combination with other lipids, dissolve this lipid separately and then combine dissolved lipids in their respective solvent solutions. |
Exact Mass |
1746.316 |
Form |
Powder |
Hygroscopic |
No |
Light Sensitive |
No |
Percent Composition |
C 65.98%, H 10.61%, N 2.40%, O 19.23%, P 1.77% |
Stability |
1 year |
Storage Temperature |
-20℃ |
Type |
TLR-4 Agonist |
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