Vaccine Lab / Alfa Chemistry
GL67

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GL67

Catalog Number ACM179075300-1
CAS 179075-30-0
Structure
Description N4-Cholesteryl-Spermine HCl Salt
N4-cholesteryl-spermine HCl salt, also known as Genzyme Lipid 67 (GL67), is a cholesterol derivatized with spermine to create a cationic lipid. GL67 has been proven to efficiently mediate gene transfer into mammalian cells and was a key formulation component that successfully completed clinical studies for the delivery of pDNA via inhalation.
Molecular Weight 724.37
Molecular Formula C38H73N4O2Cl3
Exact Mass 722.48
Form Powder
Hygroscopic No
Light Sensitive No
Stability 1 Year
Storage Temperature -20℃
Knowledge & Learning Case Study Q&A

Common Cationic Lipids and Their Applications in Vaccines

Messenger RNA (mRNA) vaccines have emerged as a groundbreaking tool in the realm of vaccine development. Unlike traditional vaccines, mRNA vaccines work by introducing genetic material encoding a specific antigen into cells, prompting the cells to produce the antigen themselves. This approach stimulates an immune response as the body identifies the antigen as foreign and generates antibodies to combat it. One of the key benefits of mRNA vaccines is their agility in design and production, allowing for rapid response to emerging threats such as viral outbreaks or mutations. Get more information on:

  • Role of mRNA in Vaccine Development
  • Importance of Cationic Lipids in mRNA Delivery
  • Cationic Lipids in mRNA Vaccine Formulations
  • Popular Cationic Lipids from Alfa Chemistry
  • Examples of Cationic Lipids Utilized in Vaccines

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