Vaccine Lab / Alfa Chemistry
Gentamicin sulfate

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Gentamicin sulfate

Catalog Number ACM1405410-2
CAS 1405-41-0
Structure
Description Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM.
Molecular Weight 561.65 (Average)
Molecular Formula C24H55N7O11S3*
Canonical SMILES O=S(O)(O)=O.O[C@]1(C)C(NC)[C@@H](O)[C@@H](O[C@H]2C(N)C[C@H](N)[C@@H](O[C@@H]3[C@H](N)CC[C@@H]([R])O3)[C@@H]2O)OC1.NC[*].C[C@H]([*])N.C[C@H]([*])NC.[R=].[or].[or]
Appearance Solid
Storage 4°C, sealed storage, away from moisture
In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
IC50&Target Aminoglycoside
Initial Source Micromonospora purpurea
Research Areas Infection
Shipping Room temperature in continental US; may vary elsewhere.
Solvent&Solubility In Vitro:
H2O : ≥ 30 mg/mL
DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
In Vivo:
1. Add each solvent one by one: PBS
Solubility: 100 mg/mL (Infinity mM); Clear solution; Need ultrasonic
Target Antibiotic; Bacterial
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