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DSPE-PEG(2000) Carboxylic Acid
Catalog Number |
ACM1403744375-3 |
CAS |
1403744-37-5 |
Structure |
|
Description |
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) The chemical name for DSPE PEG 2000 Carboxylic Acid is 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) or DSPE-PEG-COOH. |
Synonyms |
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[acetyl-(polyethylene glycol)-2000-O-acetic acid] (sodium salt) |
Molecular Weight |
2780.38 |
Molecular Formula |
C131H257NNaO55P (average MW due to polydispersity of PEG) |
Purity |
>98% |
Application |
The DSPE's hydrophobic characteristics facilitate the encapsulation and gathering of other hydrophobic drugs. In the presence of an activator like EDC or HATU, the -COOH group can readily react with primary amines, resulting in the formation of a stable amide bond. DSPE-PEG 2000 carboxylic acid has been utilized to attach ITGA2 antibodies to liposome surfaces, create atosiban-conjugated liposomes, and produce dual complementary liposomes. |
Exact Mass |
2778.7 |
Form |
Powder |
Hygroscopic |
Yes |
Light Sensitive |
No |
Percent Composition |
C 56.59%, H 9.32%, N 0.50%, Na 0.83%, O 31.65%, P 1.11% |
Stability |
1 Year |
Storage Temperature |
-20℃ |
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