Vaccine Lab / Alfa Chemistry
DSPE-PEG(2000) Carboxylic Acid

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DSPE-PEG(2000) Carboxylic Acid

Catalog Number ACM1403744375-3
CAS 1403744-37-5
Structure
Description 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)
The chemical name for DSPE PEG 2000 Carboxylic Acid is 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) or DSPE-PEG-COOH.
Synonyms 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[acetyl-(polyethylene glycol)-2000-O-acetic acid] (sodium salt)
Molecular Weight 2780.38
Molecular Formula C131H257NNaO55P (average MW due to polydispersity of PEG)
Purity >98%
Application The DSPE's hydrophobic characteristics facilitate the encapsulation and gathering of other hydrophobic drugs. In the presence of an activator like EDC or HATU, the -COOH group can readily react with primary amines, resulting in the formation of a stable amide bond.
DSPE-PEG 2000 carboxylic acid has been utilized to attach ITGA2 antibodies to liposome surfaces, create atosiban-conjugated liposomes, and produce dual complementary liposomes.
Exact Mass 2778.7
Form Powder
Hygroscopic Yes
Light Sensitive No
Percent Composition C 56.59%, H 9.32%, N 0.50%, Na 0.83%, O 31.65%, P 1.11%
Stability 1 Year
Storage Temperature -20℃
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