Vaccine Lab / Alfa Chemistry
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

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1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

Catalog Number ACM474943276
CAS 474943-27-6
Synonyms 18:0-22:6 PG
IUPAC Name Sodium;2,3-dihydroxypropyl [(2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl]oxy-3-octadecanoyloxypropyl] phosphate
Molecular Weight 845.1
Molecular Formula C46H78NaO10P
Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(CO)O)OC(=O)CCC=CCC=CCC=CCC=CCC=CCC=CCC.[Na+]
InChI InChI=1S/C46H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-20-21-22-24-26-28-30-32-34-36-38-46(50)56-44(42-55-57(51,52)54-40-43(48)39-47)41-53-45(49)37-35-33-31-29-27-25-23-18-16-14-12-10-8-6-4-2;/h5,7,11,13,17,19,21-22,26,28,32,34,43-44,47-48H,3-4,6,8-10,12,14-16,18,20,23-25,27,29-31,33,35-42H2,1-2H3,(H,51,52);/q;+1/p-1/b7-5-,13-11-,19-17-,22-21-,28-26-,34-32-;/t43,44-;/m1./s1
InChI Key MZXILCJOOQSOIZ-DTRIVZRESA-M
Purity 99%+
Complexity 1180
Covalently-Bonded Unit Count 2
Defined Atom Stereocenter Count 1
Exact Mass 844.52302996
Heavy Atom Count 58
Hydrogen Bond Acceptor Count 10
Hydrogen Bond Donor Count 2
Isomeric SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC(CO)O)OC(=O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC.[Na+]
Monoisotopic Mass 844.52302996
Physical State Liquid
Rotatable Bond Count 42
Storage Conditions -20 °C
Topological Polar Surface Area 152 Ų
Knowledge & Learning Case Study Q&A

The Composition and Role of Phosphatidylglycerol in Liposome Technology

Phosphatidylglycerol (PG) is a type of phospholipid that plays a crucial role in cell membrane structure and function. It consists of two fatty acid chains linked to a glycerol backbone, with a phosphate group and a small polar head group attached to one end. PG is a significant component of bacterial membranes, particularly in cytoplasmic membranes and chloroplast thylakoid membranes. Structurally, PG contributes to the fluidity and stability of cell membranes, influencing various cellular processes. Get more information on:

  • What Is Phosphatidylglycerol?
  • Phosphatidylglycerol Liposomes
  • Selected Phosphatidylglycerol Series from Alfa Chemistry
  • Applications of Phosphatidylglycerol Liposomes

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