Vaccine Lab / Alfa Chemistry
1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

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1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

Catalog Number ACM384833221
CAS 384833-22-1
Synonyms 16:0-22:6 PG
IUPAC Name Sodium;2,3-dihydroxypropyl [(2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyl]oxy-3-hexadecanoyloxypropyl] phosphate
Molecular Weight 817
Molecular Formula C44H74NaO10P
Canonical SMILES PPLIUYJYDZUMAR-DDKPFXSLSA-M
InChI InChI=1S/C44H75O10P.Na/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-44(48)54-42(40-53-55(49,50)52-38-41(46)37-45)39-51-43(47)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2;/h5,7,11,13,17-18,20-21,24,26,30,32,41-42,45-46H,3-4,6,8-10,12,14-16,19,22-23,25,27-29,31,33-40H2,1-2H3,(H,49,50);/q;+1/p-1/b7-5-,13-11-,18-17-,21-20-,26-24-,32-30-;/t41,42-;/m1./s1
InChI Key PPLIUYJYDZUMAR-DDKPFXSLSA-M
Purity 99%+
Complexity 1150
Covalently-Bonded Unit Count 2
Defined Atom Stereocenter Count 1
Exact Mass 816.49172983
Heavy Atom Count 56
Hydrogen Bond Acceptor Count 10
Hydrogen Bond Donor Count 2
Isomeric SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC(CO)O)OC(=O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC.[Na+]
Monoisotopic Mass 816.49172983
Physical State Liquid
Rotatable Bond Count 40
Storage Conditions -20 °C
Topological Polar Surface Area 152 Ų
Knowledge & Learning Case Study Q&A

The Composition and Role of Phosphatidylglycerol in Liposome Technology

Phosphatidylglycerol (PG) is a type of phospholipid that plays a crucial role in cell membrane structure and function. It consists of two fatty acid chains linked to a glycerol backbone, with a phosphate group and a small polar head group attached to one end. PG is a significant component of bacterial membranes, particularly in cytoplasmic membranes and chloroplast thylakoid membranes. Structurally, PG contributes to the fluidity and stability of cell membranes, influencing various cellular processes. Get more information on:

  • What Is Phosphatidylglycerol?
  • Phosphatidylglycerol Liposomes
  • Selected Phosphatidylglycerol Series from Alfa Chemistry
  • Applications of Phosphatidylglycerol Liposomes

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